Hypoxia during Thoracic Surgery

Effect of thoracic epidural blockade on hypoxia-induced pulmonary arterial hypertension in rats

Objective(s): The present study was aimed to investigate the influence of thoracic epidural blockade on hypoxia-induced pulmonary hypertension in rats. Materials and Methods: Forty eight Wistar rats were randomly divided into 4 equal groups, named normoxia hypoxia hypoxia/ ropivacaine and hypoxia/saline. Animals were placed in a hypoxia chamber and instrumented with epidural catheters at the t...

Evaluation of Intraoperative Complications in Pericardiectomy with Transdiaphragmatic Thoracoscopic Approach in Dog

Objectives- Recording intraoperative cardiorespiratory events in thoracoscopic total pericardiectomy via transdiaphragmatic camera port in dog to evaluate feasibility and risks of mechanical stimulation of pherenic nerve during this surgical approach.Design- Technical assessment, experimental study.Animals- Nine healthy, male mixed breed dogs.Procedures- Under one lung ventilation inhalation ge...

Surgery for multiple and diffuse pulmonary arteriovenous fistulas during childhood.

We report an uncommon clinical case of multiple, diffuse pulmonary arteriovenous fistulas that occurred during childhood. A 15-year-old Japanese girl with multiple pulmonary arteriovenous fistulas presented with moderate hypoxemia and was treated by left lower lobectomy for complete resection of the arteriovenous fistulas. Clinical and radiographic features are presented.

Bosentan prevents hypoxia-reoxygenation-induced pulmonary hypertension and improves pulmonary function.

BACKGROUND Acute hypoxia results in increased pulmonary vascular resistance. Despite reoxygenation, pulmonary vascular resistance remains elevated and pulmonary function is altered. Endothelin-1 might contribute to hypoxia-reoxygenation-induced pulmonary hypertension and to reoxygenation injury by stimulating leukocytes. This study was carried out using an established model of hypoxia and reoxy...

Asynchronous independent intermittent positive pressure ventilation as a solution to refractory hypoxemia during chest surgery.